Ototoxic Drugs

Tinnitus is a potential side-effect of many prescription medications. However, in most cases and for most drugs, tinnitus is an acute, short-lived side-effect; if the patient stops taking the medication, the tinnitus symptoms typically recede.

Some drugs that can cause or worsen tinnitus:

  • Aspirin and other Non-Steroidal Anti-Inflammatory Drugs (NSAIDs), including ibuprofen and naproxen.
  • Certain Antibiotics, including ciprofloxacin, doxycycline, gentamicin, erythromycin, tetracycline, tobramycin, and vancomycin.
  • Certain Cancer medications, including cisplatin and vincristine.
  • Loop Diuretics (when given intravenously in high doses).
  • Tricyclic Antidepressants such as amitriptyline, clomipramine, and imipramine.
  • Antimalarial Drugs such as chloroquine and quinine
  • Certain Anticonvulsants, including carbamazepine and valproic acid.

If you are worried about tinnitus as a side effect of your medications, please consult your subscribing Doctor. You should not stop taking any medication without first consulting with your healthcare provider. The risks of stopping a medication may far exceed any potential benefit.